At-Home

Participate from the Comfort of Your Own Home

Not close to a recruiting site? No problem, participation is now also available from the comfort of your own home.

Are you interested in learning more about participating from the comfort of your own home? You can now participate in an At-Home Epeleuton clinical trial to assess a novel treatment of Sickle Cell Disease.

Complete the form below OR call us at 833-278-2656

At-Home Clinical Trial FAQ

The purpose of this study is to assess how orally administered Epeleuton capsules are processed in the body, how Epeleuton targets different aspects of Sickle Cell Disease and how well Epeleuton is tolerated.
You will be asked questions about your condition and sickle cell diagnosis on the phone. If the information you provide suggests that you might be eligible, the information will be provided to the study doctor and staff who will then follow up with you to schedule a more detailed assessment to confirm your eligibility.
Upon completion of the study eligibility assessments, such as bloods at your first study visit, your study doctor will call you to inform you of the result of these enquiries and the study nurse will then reach out to you to set up your next at-home visit.
There is no requirement for any medical equipment at your home. All equipment will be taken care of by the study doctor and nurses who will travel to your home.
  • You will be taking Epeleuton capsules twice daily for 4 months.
  • You will facilitate just 6 visits in the comfort of your home.
  • You will undergo blood draws at each of those visit.
  • You will be asked to maintain a daily electronic Diary on your personal device (phone, tablet, etc.).
Yes, you will be asked to attend 5 video calls with the medical staff from Science 37 where they will ask you questions about your wellbeing and around taking of the Epeleuton capsules.
Each video call will be scheduled at the time that is suitable for you and medical staff and at frequency established by the clinical protocol for this study.
Yes, the study procedures at home will be the same as if you were in the clinic.
You can notify the medical staff who set up the visit date with you and they will arrange a date suitable for both parties.
You can reach out to your Science 37 representative via phone, email, or text message. They are there to assist you with will any questions or concerns and will be sure to communicate them with your study doctor. If needed, a phone call can be set up with the study doctor.
Epeleuton’s active ingredient is a fatty acid, 15-hydroxy eicosapentaenoic acid (15(S)-HEPE) ethyl ester. 15(S)-HEPE is found naturally in the body. In previous preclinical studies it has been shown to have a positive effect on the health of red blood cells and hemolytic anemia (when red blood cells are destroyed faster than they can be made), on blood vessel inflammation and on organ damage.
Epeleuton capsules need to be taken by mouth, with food or within 30 minutes of a meal, twice daily.
The study medication will be sent directly to your home in advance of your visits.
Epeleuton capsules need to be stored in the fridge.
Science 37 is the name of the organization providing this at-home trial option. Dr. Shaalan Beg is the main study doctor from Science 37 for this clinical trial and he is joined by other medical staff to conduct the at-home visits for the study. Science 37 has conducted many at-home studies, including studies in children, adolescents, and young adults.
Afimmune is a clinical stage, biopharmaceutical drug discovery company focused on the development of new therapies for rare blood disorders.